Are there any long term effects from over the counter sleep aids (antihistamines), kidney or liver?

Antihistamines used as sleep aids (e.g. diphenhydramine) can have some effects on people with health problems such as epilepsy, asthma, glaucoma, cardiac arrhythmia, or an enlarged prostate.

Diphenhydramine should not have negative impact on liver or kidney, however may cause some urinary problems including bladder obstruction.

Every single medication including over the counter and even herbs have different side effects, so you just have to look them up individually.

Anyway, you should not be using this sleep meds for prolonged time without consulting your doctor. These drugs are intended for occasional sleeping difficulties. Your doctor knows better your health condition and will be able to help you with the best treatment option.
I hope this will help you.

Check also this link:
http://www.the-sleep-zone.com/overthecountersleepaids.html

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